Playing is easy enough since most people at your party will already know how to play. Before the game divide up into teams and encourage everyone of all ages to participate. If you have kids playing you can play a lighthearted game of flag or (soft)touch football, if it’s just the guys, go all out with a rough and tumble game of football.
It is not so much about who wins as it is about getting everyone’s blood pumping so when it is finally time for Super Bowl kick off (pregame seems to last for days) people are excited and ready for some football. If some people really do not want to play, get them to coach, referee or be cheerleaders. Try and get the whole party involved in some way, your neighbors may even want to join in when they see all the fun you are having!
If you plan for this in advance you can let you guests know so they can bring a quick change of clothes and/or shoes, too.